stages of scleroderma
Scleroderma is a long-lasting disease that affects your skin, connective tissue, and internal organs.It happens when your immune system causes … Systemic scleroderma is an autoimmune disease that affects the skin and internal organs. Years ago, only the worst cases of systemic sclerosis (scleroderma) were diagnosed, thus leading to the widespread belief that systemic scleroderma was always progressive and fatal.. Now that the full range of types and severity of scleroderma are being recognized and diagnosed, there is increasing awareness that many people have a milder type of illness with a … Some people have a type of scleroderma called CREST syndrome (or limited scleroderma). Overview. Although it most often affects the skin, scleroderma also can affect many other parts of the body. Alopecia (hair loss) may occur with scleroderma… SS may only affect the skin in the early stages of the disease. The skin changes associated with limited scleroderma typically occur only in the lower arms and legs, below the elbows and knees, and sometimes affect the face and neck. In the earliest stages of scleroderma, the skin appears mildly inflamed with swelling and often redness. Pictures of Systemic Sclerosis (Scleroderma) Symptoms of Systemic Sclerosis. A survival study of patients with scleroderma diagnosed over 30 years (1953-1983): the value of a simple cutaneous classification in the early stages of the disease. One hundred and thirteen died from isolated pulmonary hypertension … Overview. Recognition of the two types of lung disease is important because their predictors and treatment differ Pulmonary disease is now the leading cause of death in patients with scleroderma. Pictures of Alopecia Scleroderma is a very rare cause of balding or hair thinning. Scleroderma is a chronic and rare type of autoimmune disease that primarily targets the skin and the body’s connective tissues. Scleroderma is a rare disease. Of the 2000 patients in the Pittsburgh scleroderma databank, 211 patients have died of lung disease over the past 20 years. Limited scleroderma, also known as CREST syndrome, is one subtype of scleroderma — a condition whose name means "hardened skin." Different symptoms may develop in stages over a very long It is characterized by scar tissue (fibrosis) on the skin and other organs. Fibrosis is caused by the production of too much collagen in the body. Diagnosis of scleroderma may be very difficult, particularly in its early stages. Collagen normally strengthens and supports connective tissues. The disease involves progressive affectation of the body through gradual hardening and tightening of the skin and connective tissues – components of the body that are naturally meant to be elastic and flexible. This video slideshow features images of scleroderma (systemic sclerosis) symptoms such as calcinosis, digital ulcers, gangrene, and Raynaud's. J Rheumatol. The most common age span for scleroderma to develop is between 35 and 50. (Also see What is Scleroderma?, Types of Scleroderma, Scleroderma Symptoms, and Scleroderma Videos). Many of its symptoms are common to, or may overlap with, those of other diseases, especially other autoimmune connective-tissue diseases such as rheumatoid arthritis and lupus. Fewer than 500,000 people in the United States have scleroderma. The skin gradually thickens (more rapidly in the diffuse form) and the patient feels progressive “tightening” of the skin with decreased flexibility. Only a few people get scleroderma, but no one really knows why. No one knows for sure why or how it develops. Some experts report that six out of seven patients are women. Scleroderma is a chronic but rare autoimmune disease in which normal tissue is replaced with thick tissue with extra collagen. Barnett AJ, Miller MH, Littlejohn GO. 1988 Feb. 15(2):276-83. .
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